Table 1.
Baseline characteristics
All (n = 998) | ‘High CRP’ (n = 375) | ‘Low CRP’ (n = 623) | p value | |
---|---|---|---|---|
Age (years) | 66 [56–74] | 66 [56–75] | 66 [56–74] | 0.349 |
Male sex (%) | 62 | 61 | 62 | 0.924 |
LOS in hospital before ICU admission | 1 [0–4] | 1 [1–4] | 1 [0–4] | 0.655 |
APACHE II score admission | 19 [15–24] | 18 [14–22] | 19 [15–25] | <0.001 |
SMR score admission | 27 [12–53] | 21 [10–41] | 32 [14–57] | <0.001 |
SOFA score admission | 7.2 (2.9) | 6.7 (2.9) | 7.5 (2.9) | <0.001 |
SAPS II score admission | 32 [26–39] | 31 [25–38] | 33 [26–42] | 0.048 |
CRP admission (mg/L) | 66 [10–178] | 57 [7–170) | 72 [15–180] | 0.046 |
WCC admission (×109) | 13.8 (8.2) | 13.0 (6.9) | 14.2 (8.9) | 0.032 |
Temp admission (°C) | 37.2 (1.2) | 37.2 (1.1) | 37.3 (1.3) | 0.144 |
Comorbidities (%) | ||||
Chronic renal failure | 8 | 8 | 7 | 0.485 |
Hypertension | 30 | 31 | 29 | 0.552 |
COPD | 20 | 20 | 19 | 0.620 |
Diabetes mellitus | 19 | 18 | 20 | 0.394 |
Chronic cardiovascular disease | 18 | 18 | 18 | 0.781 |
Cancer | 15 | 14 | 15 | 0.597 |
Other | 6 | 6 | 7 | 0.534 |
Diagnosis group (%) | ||||
Elective surgery | 12 | 20 | 8 | |
Cardiac surgery | 26 | 31 | 23 | |
Sepsis | 38 | 32 | 41 | |
Trauma | 2 | 2 | 2 | |
Cardiac arrest | 8 | 7 | 9 | <0.001 |
CFH | 5 | 3 | 6 | |
COPD | 2 | 1 | 2 | |
Intoxication | 2 | 1 | 2 | |
Metabolic | 1 | 1 | 2 | |
Others | 4 | 3 | 5 | |
Type of admission (%) | ||||
Medical | 43 | 31 | 50 | |
Surgical—planned | 31 | 42 | 25 | <0.001 |
Surgical—urgent | 26 | 27 | 25 | |
Patient’s origin (%) | ||||
Emergency department | 23 | 20 | 25 | |
Ward | 19 | 12 | 23 | <0.001 |
Operating room | 54 | 66 | 47 | |
Other hospital | 4 | 2 | 5 |
Data are presented as mean ± SD (normal distribution), as median with interquartile range (non-normal distribution) or as % (categorical variable)
CRP C-reactive protein; high CRP, CRP ≥75 mg/L; low CRP, CRP <75 mg/L; LOS length of stay; APACHE II, Acute Physiology and Chronic Health Evaluation II; SMR standardized mortality rate; SOFA Sequential Organ Failure Assessment; SAPS II Simplified Acute Physiology Score II; WCC white cell counts; Temp body temperature; COPD chronic obstructive pulmonary disease; CFH congestive heart failure