Table 2.
Primary and secondary outcomes
| All (n = 998) | ‘High CRP’ (n = 375) | ‘Low CRP’ (n = 623) | p value | |
|---|---|---|---|---|
| Readmission (%) | 9.5 | 13.1 | 7.4 | 0.003 |
| In-hospital mortality (%) | 5.5 | 6.9 | 4.7 | 0.127 |
| Adverse outcome (%) | 13.4 | 17.9 | 10.1 | 0.001 |
| CRP discharge (mg/L) | 58 [33–102] | 115 [93–161] | 39 [19–55] | <0.001 |
| WCC discharge (×109) | 12.4 (5.7) | 13.3 (5.7) | 11.9 (5.6) | <0.001 |
| Temp discharge (°C) | 37.1 (1.3) | 37.2 (1.1) | 37.0 (1.4) | 0.068 |
| SOFA score discharge | 3.0 (1.8) | 3.3 (1.9) | 2.9 (1.7) | <0.001 |
| LOS ICU (days) | 7 [5–12] | 6 [4–8] | 9 [6–16] | <0.001 |
| Mechanical ventilation (%) | 94 | 95 | 93 | 0.233 |
| Days of mechanical ventilation (n) | 3 [1–6] | 2 [1–4] | 4 [1–7] | <0.001 |
| Renal support (%) | 14 | 9 | 17 | <0.001 |
| Destination (%) | ||||
| Ward | 96 | 99 | 95 | |
| Home | 1 | 0 | 1 | 0.004 |
| Nursing/rehabilitation center | 3 | 1 | 4 | |
| LOS hospital after ICU discharge (days) | 9 [5–16] | 9 [6–16] | 9 [5–16] | 0.404 |
Data are presented as mean ± SD (normal distribution), as median with interquartile range (non-normal distribution) or as % (categorical variable)
CRP C-reactive protein; high CRP, CRP ≥75 mg/L; low CRP, CRP <75 mg/L; adverse outcome, intensive care unit readmission and/or in-hospital mortality; WCC white cell counts; Temp body temperature; SOFA Sequential Organ Failure Assessment; LOS length of stay; ICU intensive care unit