Table 2.
Microstructure analysis | Vehicle | SB-742457 | ||
---|---|---|---|---|
3.0 mg/kg | 10 mg/kg | 30 mg/kg | ||
Number of licks | 1456.7 (199.9) | 992.8* (255.2) | 1130.7 (249.9) | 1238.9 (278.4) |
Bout duration (s) | 2.7 (0.5) | 1.9 (0.1) | 2.1 (0.3) | 2.0 (0.3) |
Bout number | 97.2 (12.8) | 73.5* (17.2) | 80.1 (13.9) | 114.5 (27.3) |
Intra-bout lick rate (licks/s) |
6.4 (0.1) | 6.4 (0.2) | 6.3 (0.2) | 5.9* (0.1) |
Latency (s) | 84.7 (46.9) | 66.1 (28.0) | 76.1 (20.7) | 62.7 (23.9) |
Asterisks indicate significantly different from vehicle control condition (*p < 0.05)