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. 2016 Jan 13;6:1527. doi: 10.3389/fmicb.2015.01527

Table 2.

Blocking of cytokine production by N- and O-linked mannans isolated from either C. albicans or C. parapsilosis sensu lato cell wall.

Cytokine stimulation by C. parapsilosis sensu stricto TNFα (%) IL-6 (%)
No mannan included 100 100
Pre-incubation with C. albicans N-linked mannan 34.4 ± 4.3 90.4 ± 5.4
Pre-incubation with C. albicans O-linked mannan 43.8 ± 7.6 99.3 ± 3.2
Pre-incubation with C. parapsilosis s. st. N-linked mannan 39.4 ± 6.3 93.3 ± 4.3
Pre-incubation with C. parapsilosis s. st. O-linked mannan 40.3 ± 6.3 101.2 ± 4.3
Pre-incubation with C. orthopsilosis N-linked mannan 33.4 ± 9.3 101.4 ± 3.4
Pre-incubation with C. orthopsilosis O-linked mannan 42.3 ± 4.9 95.8 ± 4.2
Pre-incubation with C. metapsilosis N-linked mannan 35.6 ± 6.6 95.3 ± 5.5
Pre-incubation with C. metapsilosis O-linked mannan 43.8 ± 3.9 100.5 ± 6.3

P< 0.05, when compared to stimulation with no mannan included.