Table 3.

Univariate Analysis (Cox Model) of Adjustment Variables (2376 Subjects, 675 Who Experienced an AIDS Event)—Aquitaine Cohort, France, 1985–1997

Variables	Categories	HR	(95% CI)	p
Gender	Male	Ref
	Female	0.73	(0.61–0.87)	<0.0001
Age		1.31a	(1.22–1.40)	<0.0001
HIV transmission category	Homosexuals	Ref
	Intravenous drug users	0.78	(0.65–0.93)	<0.001
	Blood recipients	1.00	(0.77–1.31)	0.99
	Heterosexuals	0.57	(0.45–0.71)	<0.0001
	Indeterminate	0.41	(0.23–0.75)	<0.01
Period of enrollment	1995–1997	Ref
	1991–1994	2.22	(1.33–3.71)	<0.01
	1987–1990	2.41	(1.44–4.04)	<0.001
	1985–1986	1.84	(0.99–3.43)	0.06
Baseline clinical stageb	A	Ref
	B	2.24	(1.87–2.68)	<0.0001
Baseline weight		0.99	(0.98–1.00)	0.04
CD4 cell count at enrollment		0.69c	(0.66–0.73)	<0.0001
Drop under 200 CD4/mm3	No	Ref
	Yes	13.3d	(10.56–16.84)	<0.0001
Antiretroviral treatment	No	Ref
	Yes	4.39d	(3.63–5.30)	<0.0001
Primary prophylaxis	No	Ref
	Yes	4.94d	(4.21–5.81)	<0.0001

^aFor increase of 10 years (continuous variable).

^bCDC clinical stage (Centers for Disease Control, 1992).

^cFor increase of 100 CD4/mm³ (continuous variable).

^dTime dependent variable.

HR = Hazard Ratio, 95% CI = 95 percent confidence interval.