Fig. 4.

Radiographic progression by categories of MBDA score and conventional measures of disease activity

Frequency of change (Δ) in total Sharp−van der Heijde score (SHS) >3 over the following year was determined for visits (N = 271) subgrouped by MBDA score [low (<30), moderate (30−44) or high (>44)] within groupings of low, moderate or high based on swollen joint count (SJC28) (A), CRP (B) or DAS28–CRP (C). Sample sizes and P-values appear in supplementary Tables S4 and S5, respectively, available at Rheumatology Online. NP: no patients in that subgroup; MBDA: multi-biomarker disease activity.