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. 2015 Dec 24;5(12):e009522. doi: 10.1136/bmjopen-2015-009522

Table 2.

Incidence rates and 95% CIs, observation time, and number of events according to exposure status

Number of events Observation time (person years) Incidence rate per 100 person years (95% CI)
Non-exposed 164.942 7.167.515 2.30 (2.29 to 2.31)
Nitrates (days)
 0–14 91 2.690 3.38 (2.75 to 4.15)
 15–30 62 2.736 2.27 (1.77 to 2.91)
 31–90 274 7.819 3.50 (3.11 to 3.94)
 91–180 294 8.973 3.27 (2.92 to 3.67)
 >180 4.155 120.238 3.46 (3.35 to 3.56)
Digoxin (days)
 0–14 156 3.739 4.17 (3.57 to 4.88)
 15–30 188 4.106 4.58 (3.97 to 5.28)
 31–90 495 12.583 3.93 (3.08 to 3.67)
 91–180 505 15.013 3.36 (3.08 to 3.67)
 >180 5.792 189.066 3.06 (2.98 to 3.14)
Thiazides (days)
 0–14 446 12.518 3.56 (3.25 to 3.91)
 15–30 518 13.414 3.86 (3.54 to 4.21)
 31–90 1.502 44.958 3.34 (3.18 to 3.51)
 91–180 1.276 46.335 2.75 (2.61 to 2.91)
 >180 18.057 687.456 2.63 (2.59 to 2.67)
ACE inhibitors (days)
 0–14 273 11.821 2.31 (2.05 to 2.60)
 15–30 330 13.092 2.52 (2.26 to 2.81)
 31–90 980 41.447 2.36 (2.22 to 2.52)
 91–180 1.124 49.915 2.25 (2.12 to 2.39)
 >180 15.910 640.066 2.49 (2.45 to 2.52)
Loop diuretics (days)
 0–14 615 11.590 5.31 (4.90 to 5.74)
 15–30 570 11.883 4.80 (4.42 to 5.21)
 31–90 1.329 30.281 4.39 (4.16 to 4.63)
 91–180 1.584 36.189 4.38 (4.17 to 4.60)
 >180 18.846 475.456 3.96 (3.91 to 4.02)
Calcium antagonists (days)
 0–14 249 10.532 2.36 (2.09 to 2.68)
 15–30 315 11.900 2.64 (2.37 to 2.96)
 31–90 926 39.813 2.33 (2.18 to 2.48)
 91–180 1.111 50.428 2.20 (2.08 to 2.34)
 >180 16.691 663.196 2.52 (2.48 to 2.56)
β-Blockers (days)
 0–14 260 10.843 2.39 (2.12 to 2.71)
 15–30 304 11.932 2.55 (2.28 to 2.85)
 31–90 974 37.562 2.59 (2.44 to 2.76)
 91–180 1.208 47.672 2.53 (2.40 to 2.68)
 >180 19.194 761.936 2.52 (2.48 to 2.56)
Statins (days)
 0–14 224 12.342 1.81 (1.59 to 2.07)
 15–30 267 14.033 1.90 (1.69 to 2.15)
 31–90 877 48.745 1.80 (1.68 to 1.92)
 91–180 1.168 62.608 1.87 (1.76 to 1.98)
 >180 22.858 1.100.165 2.08 (2.05 to 2.10)
Angiotensin receptor antagonists (days)
 0–14 131 5.897 2.22 (1.87 to 2.64)
 15–30 129 6.185 2.09 (1.75 to 2.48)
 31–90 379 19.938 1.90 (1.72 to 2.10)
 91–180 556 26.130 2.12 (1.96 to 2.31)
 >180 7.636 333.944 2.29 (2.24 to 2.34)