Table 1.
Characteristics of SMA children and SMN2 methylation according to their clinical types
| Type | Age (year) | Gender male/female | Methylation (%) |
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| CGI 1 | CGI 2 | CGI 3 | CGI 4 | |||
| SMA I (n=12) | 0.6±0.5 | 8/4 | 76.7±8.6 | 59.9±5.0 | 13.5±4.6 | 70.0±3.8 |
| SMA II (n=15) | 1.3±1.1 | 7/8 | 79.6±3.9 | 58.6±3.5 | 13.1±3.1 | 73.4±6.3 |
| SMA III (n=8) | 2.9±1.3 | 4/4 | 77.8±3.1 | 56.8±2.8 | 12.8±1.7 | 68.0±1.7 |
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| P-value | 0.000 | 0.558 | 0.453 | 0.236 | 0.916 | 0.032 |
| Adjusted P-value | 0.474 | 0.098 | 0.824 | 0.014 | ||
Results are shown as mean±standard deviation (SD) unless otherwise stated. Statistically significant results are shown in bold. The P-value was obtained by performing an ANOVA test or chi-square test when appropriate. The adjusted P-value was obtained by an analysis of covariance and age was considered as the co-variable