Table 2. Formulations and Luciferase Expression of Mice Treated with Polyplexes via Hydrodynamic Injectionsa.
sample | formulation | dose pDNA (μg) | luminescence 24 h (photons/s) | luminescence 48 h (photons/s) |
---|---|---|---|---|
Glycofect | N/P: 3 | 10 | 2.50 × 109* | 1.39 × 109* |
jetPEI | N/P: 7 | 10 | 3.70 × 107* | 8.52 × 107* |
jetPEI | N/P: 3 | 25 | 4.53 × 108* | 1.64 × 108* |
pMAT-b-AEMA-2 | N/P: 3 | 10 | 4.39 × 1010 | 2.29 × 1010 |
pDNA | N/A | 10 | 3.95 × 1010 | 8.93 × 109 |
Luminescence levels were averaged from the values obtained from 3 mice in each data set and are reported in photons/s. The logarithm of each measurement was calculated and samples that were found to be statistically different from pMAT-b-AEMA-2 were marked with an * (according to Student’s t-test with p < 0.05).