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. 2015 Dec 30;2016:3423267. doi: 10.1155/2016/3423267

Figure 7.

Figure 7

Developmental changes in the amplitude and frequency of spontaneous excitatory postsynaptic currents (EPSCs; downward deflections) in hypoglossal motoneurons recorded from the C57/Bl6 WT mice (a), compared to the mice overexpressing the mutated human SOD1G93A gene (b) at P0, P15, and P30. The amplitude of EPSCs increased by ~3-fold, while the frequency of EPSCs reduced by ~50% with postnatal maturation (from P0 to P30) in WT mice. In the mutated hSOD1G93A mice the frequency of EPSCs was increased, without a clear change in EPSC amplitude, compared to age-matched WT littermates. Scale bars = 100 pA, 0.1 s.