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. 2016 Jan 13;17:50. doi: 10.1186/s12864-016-2383-1

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© Kučerová et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Altered gene expression in Toll (Tl) signaling pathway during diapause. The scheme displays a generalized assembly (regardless tissue specificity) of relevant genes in the Toll signal pathway. Transcript levels (logarithmic fold change, LogFC) are given in red for upregulated, blue for downregulated and black for no significant change (ns; LogFC close to 0). The acronyms are listed in Additional file 6: Table S3 where also references and details of gene/protein functions are given. The Toll pathway is activated in diapausing flies as seen from increases of target genes such as Drosomycin (Drs), Drosomycin-like 5 (Drsl5), IM1 and IM2. Also several extracellular members of the Toll-activating proteolytic cascade were upregulated. The signaling scheme is based on [97]