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. 2016 Jan 13;17:50. doi: 10.1186/s12864-016-2383-1

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© Kučerová et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Altered gene expression in the JNK signaling pathway during diapause. This scheme displays a generalized assembly (regardless tissue specificity) of relevant genes in the JNK signal pathway. Transcript levels (logarithmic fold change, LogFC) are given in red for upregulated, blue for downregulated and black for no significant change (ns; LogFC close to 0). The acronyms are listed in Additional file 6: Table S3 where also references and details of gene/protein functions are given. At the whole organism level diapausing flies demonstrate a moderate activation of JNK signaling as judged from an elevated expression of some target genes. There is also enhanced expression of JNK-responsive genes, known to be under FOXO (IIS) transcriptional control (Sesn and Fer1HCH)