Table 1.
Patient characteristics
| Characteristics | Healthy (n = 5) | ACPE (n = 6) | Mild ARDS (n = 9) | Moderate/severe ARDS (n = 13) |
|---|---|---|---|---|
| Age, yr | 38 [34–43] | 72 [68–82] | 57 [42–71] | 58 [56–76] |
| Sex, M/F, n | 2/3 | 3/3 | 4/5 | 9/4 |
| Septic shock, n | – | – | 5 | 10 |
| SAPS II at admission | – | 24 [21–26] | 52 [49–57] | 53 [46–57] |
| PaO2/FiO2,a mmHg | – | 145 [130–201] | 220 [202–223] | 105 [98–122] |
| PEEP,a mmHg | – | 5 [5–7] | 5 [5–7] | 8 [8–12] |
| Lung Injury Scorea | – | – | 1.5 [1.25–1.75] | 2.25 [2–2.25] |
| Causes of ARDS/ALI, n | ||||
| Direct | – | – | 6 | 8 |
| Pneumonia | 5 | 7 | ||
| Gastric inhalation | 1 | 1 | ||
| Indirect | – | – | 3 | 5 |
| Pancreatitis | 2 | 2 | ||
| Intra-abdominal infection | 1 | 3 |
ACPE acute cardiogenic pulmonary edema, ALI acute lung injury, ARDS acute respiratory distress syndrome, FiO 2 fraction of inspired oxygen, PaO 2 partial pressure of oxygen in arterial blood, PEEP positive end-expiratory pressure, SAPS II Simplified Acute Physiology Score II
Results are expressed as median [IQR] unless otherwise indicated
aLower PaO2/FiO2 ratio during the first 48 h