TABLE 1.
Components of DTaP and DTwP vaccines used in this study
| Component | Amount of each component in: |
|||
|---|---|---|---|---|
| Daptacel | Triple Antigen | DT-COQ | Quinvaxem | |
| Diphtheria toxoida | 15 | 20–30 | ≥30 | ≥30 |
| Tetanus toxoida | 5 | 5–25 | ≥60 | ≥60 |
| Whole-cell B. pertussis (IU) | ≥4 | ≥4 | ≥4 | |
| Inactivated pertussis toxin (μg) | 10 | |||
| Filamentous hemagglutinin (μg) | 5 | |||
| Pertactin (μg) | 3 | |||
| Fimbriae types 2 and 3 (μg) | 5 | |||
| Other components | 10 μg Hib oligosaccharide conjugated to ∼25 μg of CRM 197, 10 μg of hepatitis B surface antigen | |||
| Aluminum (Al3+) content (mg) | 0.33 from aluminum phosphate | ≤1.25 from aluminum phosphate | 0.6 from aluminum hydroxide | 0.3 from aluminum phosphate |
a
Measured in limit of flocculation (Lf) for Daptacel and Triple Antigen and in international units for DT-COQ and Quinvaxem.