Figure 3.

Human leucocyte antigen (HLA) class I‐restricted expansion of latent membrane protein (LMP)2A‐specific interferon (IFN) γ⁺CD8⁺ T cells. (a) Percentages of total HLA class I‐restricted LMP2A‐specific CD8⁺ T cell responses generated in vitro from healthy Epstein–Barr virus (EBV) seropositive HLA‐A*02 heterozygotes (n = 9). Only HLA‐A*02‐restricted responses were significantly above zero. (b) The combined expansion of LMP2A‐specific IFN‐γ⁺CD8⁺ T‐cells is shown for all donors from the three HLA‐A*02 heterozygote combinations. Each bar depicts the percentage of LMP2A‐specific IFN‐γ⁺CD8⁺ T cells expanded from one of the six peptide pools. The peptide pools are described in Supporting information, Table S2.