Fig. 1.

Phenotype of Jak2 G−/− female mice [13]. a Vaginal opening was examined daily from 20 days of age in both control and Jak2 G−/− female mice and the day of opening was documented and average values displayed. Significance is indicated. b Female mice were mated with wild-type male mice for 90 days. Total numbers of litters per female was significantly reduced in Jak2 G−/− mice compared to control group during the 90 days. c Number of pups per litter was significantly reduced in Jak2 G−/− female mice compared to controls. For a–c, values are mean ± SEM and significance and numbers of animals examined are indicated