Skip to main content
. 2013 Nov 29;2(2):109–114. doi: 10.15420/aer.2013.2.2.109

Figure 1: Natriuretic Peptides and their Respective Receptors.

Figure 1:

Binding of NPR-A with its ligand (ANP or BNP) increases production of cyclic guanosine monophosphate. NPR-C binds with high affinity to all three NPs and facilitates their clearance from the circulation through receptor-mediated internalisation and degradation. ANP = atrial natriuretic peptide; BNP = B-type natriuretic peptide; cGMP = cyclic guanosine monophosphate; CNP = C-type natriuretic peptide; NPR-A = natriuretic peptide receptor-A; NPR-B = natriuretic peptide receptor-B; NPR-C = natriuretic peptide receptor-C; GTP = guanosine triphosphate.