TABLE II.
Anomalous difference density and 2Fo-Fc density peak heights (as a multiple of σ or rms, respectively) for each platinum atom per dataset at the Nδ and Nε binding sites.
| Nδ binding site | Nε binding site | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pt 1 | Pt 2 | Pt 1 | Pt 2 | Pt 3 | Pt 4 | |||||||
| Anom | 2Fo-Fc | Anom | 2Fo-Fc | Anom | 2Fo-Fc | Anom | 2Fo-Fc | Anom | 2Fo-Fc | Anom | 2Fo-Fc | |
| Cisplatin HEWL crystal at 150 K | 17 | 14 | 6.1 | 5.6 | 7.1 | 4.4 | 7.6 | 3.7 | 45 | 32 | 19 | 15 |
| Cisplatin HEWL crystal at 200 K | 15 | 22 | 6.1 | 11 | 9.1 | 16 | 4.8 | 5.6 | ||||
| Cisplatin HEWL crystal at RT | 4.6 | 9.0 | 4.6 | 7.5 | 2.9 | 11 | ||||||
| Carboplatin HEWL crystal at 200 K | 3.9 | 4.6 | 8.5 | 11.1 | 6.9 | 5.0 | ||||||