Table 1. Clinical characteristics of enrolled subjects.
HC | SIRS | Sepsis | P | |
---|---|---|---|---|
Numbers | 18 | 19 | 34 | |
Age (years) | 35±10 | 53±17 | 49±14 | 0.12 |
Sex (male/female) | 10/8 | 11/8 | 18/16 | 0.93 |
SOFA score | — | 3.5±1.9 | 10.7±4.1 | <0.01 |
Site of infection | ||||
Lung | — | — | 20 (58.8%) | — |
Abdomen | — | — | 11 (32.3%) | — |
Urinary tract | — | — | 3 (8.9%) | — |
Pathogen culture | — | |||
Gram− bacterial | — | — | 18 (52.9%) | — |
Gram+ bacterial | — | — | 7 (20.5%) | — |
Fungi | — | — | 2 (5.9%) | — |
Negative culture | — | — | 7 (20.7%) | — |
WBC (×109/l) | — | 14.4±3.2 | 15.9±5.9 | 0.57 |
Mechanical ventilation (n) | 3 | 12 | 0.13 | |
Renal replacement therapy (n) | — | 1 | 8 | 0.17 |
Mortality (survival/non-survival) | — | 0% (0/19) | 52.9% (16/18) | <0.01 |
Abbreviations: HC, healthy control; SIRS, systemic inflammatory response syndrome; SOFA, sepsis-related organ failure assessment; WBC, white blood cell.
Data are shown as number (%) or mean±s.d.