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. 2015 Oct 27;6:8692. doi: 10.1038/ncomms9692

Figure 2. Pharmacokinetic analysis of nanoparticle shows extended microvasculature half-life and heterogeneous tissue accumulation.

Figure 2

(a) Nanoparticle concentrations are monitored (a) and quantified (b) using time-lapse confocal fluorescence microscopy in the dorsal window chamber model. Nanoencapsulation extends the TMV half-life to 55 min, a >5-fold increase compared with unencapsulated Pt(II) compounds in the same animal model29. Scale bar, 50 μm. Thick lines and shading denote means±s.e.m. (n=6).