Fig 6. Continuous exposure to antibodies enhances antiviral activity of κFGF-MTS-anti-p24 mAbs.

Cells were incubated with 10 μg/mL of κFGF-MTS-anti-p24 mAb, native anti-p24 mAb, and unrelated κFGF-MTS-anti-AchE mAb at 37°C for 18 h. Cells were then washed and infected with HIV-1 NL4.3 at MOI 0.1 for 2 h. Complete culture medium containing 10 μg/mL of antibodies was added and cells incubated for 48 h after which culture supernatants were collected and used to infect MAGI cells. Two days after infections, MAGI cells were fixed, stained and blue foci counted. The results are representative of three independent experiments each done in duplicate.