Table 1. Cell-penetrating peptides (CPPs) used for cell internalizing antibody engineering.
| Peptide | Sequence | Size kDa) | pH | pI | Charge |
|---|---|---|---|---|---|
| BMV Gag | KMTRAQRRAAARRNRWTAR | 2.36 | Basic | 13.3 | 8 |
| FHV Coat | RRRRNRTRRNRRRVR | 2.16 | Basic | 13.5 | 11 |
| HIV-1D-Tat | GRKKRRQRRRPPQ | 1.72 | Basic | 13.2 | 8 |
| HIV-R9-Tat | GRRRRRRRRRPPQ | 1.80 | Basic | 13.4 | 9 |
| HTLV-II Rex | TRRQRTRRARRNR | 1.78 | Basic | 13.4 | 8 |
| κFGF-MTS | KAAVALLPAVLLALLP | 1.57 | Basic | 9.69 | 1 |
| Penetratin | RQIKIWFQNRRMKWKK | 2.25 | Basic | 12.8 | 7 |
| sC3d-P16 | KNRWEDPGKQLYNVEA | 1.95 | Neutral | 6.62 | 0 |
Physicochemical properties of CPPs were analyzed by online tool ‘Peptide Property Calculator’. Source: https://www.genscript.com/ssl-bin/site2/peptide_calculation.cgi