Fig. S4.

Mutational profile of biopsies containing outlier clones in patient PD18003. Mutational profile of the seven mutant clones (denoted by **) in patient PD18003 considered as outliers by size and contained within six biopsies with the specific mutant genes marked in red. Large mutant clones with similar sizes (also marked in red) are likely to represent subclones of the outlier mutant clone. Nonpoint mutations are marked in gray.