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. 2015 Dec 17;113(1):182–187. doi: 10.1073/pnas.1515617113

Table S1.

IC50 values of Lys01 in the panel of 47 cell lines

Cell line KRAS mutation status Lys01 IC50, μM
786-O Wild type 13.8
A2058 Wild type 8.2
A2780 Wild type 12.7
A-498 Wild type 6.2
A549 Mutant 30.0
BT-549 Wild type 10.7
COR-L23 Mutant 30.0
G-401 Wild type 3.7
GP2d Mutant 11.1
H4 Wild type 6.0
HCC-15 Wild type 21.8
HCC1806 Wild type 21.8
HCC-44 Mutant 25.0
HCT 116 Mutant 21.1
HEC-151 Wild type 14.6
HEC-50B Mutant 19.5
Hep3B Wild type 9.6
Hey-A8 Mutant 12.2
HMC-1–8 Mutant 13.7
HPAC Mutant 17.5
HT-29 Wild type 15.4
HuH-7 Wild type 4.3
Ishikawa Wild type 11.3
JHH-7 Wild type 8.4
JHOM-1 Wild type 17.1
JHOS-2 Wild type 22.5
KMRC-20 Wild type 12.0
KNS-62 Wild type 22.4
KP-1NL Mutant 27.7
KP4 Mutant 30.0
KYSE-150 Wild type 23.7
LCLC-103H Wild type 16.7
LK-2 Wild type 16.0
MIA PaCa-2 Mutant 17.0
NCI-H1299 Wild type 28.8
NCI-H838 Wild type 24.9
OVISE Wild type 30.0
PaTu-8988T Mutant 30.0
PC-14 Wild type 13.5
RD Wild type 11.9
RKO Wild type 16.6
RMUG-S Wild type 12.1
SK-HEP-1 Wild type 21.8
SW480 Mutant 21.8
TYK-nu Wild type 5.2
U-251 MG Wild type 15.8
VMRC-RCW Wild type 9.4

IC50 proliferation values of Lys01 correspond to Fig. 1A.