Table S1.
Cell line | KRAS mutation status | Lys01 IC50, μM |
786-O | Wild type | 13.8 |
A2058 | Wild type | 8.2 |
A2780 | Wild type | 12.7 |
A-498 | Wild type | 6.2 |
A549 | Mutant | 30.0 |
BT-549 | Wild type | 10.7 |
COR-L23 | Mutant | 30.0 |
G-401 | Wild type | 3.7 |
GP2d | Mutant | 11.1 |
H4 | Wild type | 6.0 |
HCC-15 | Wild type | 21.8 |
HCC1806 | Wild type | 21.8 |
HCC-44 | Mutant | 25.0 |
HCT 116 | Mutant | 21.1 |
HEC-151 | Wild type | 14.6 |
HEC-50B | Mutant | 19.5 |
Hep3B | Wild type | 9.6 |
Hey-A8 | Mutant | 12.2 |
HMC-1–8 | Mutant | 13.7 |
HPAC | Mutant | 17.5 |
HT-29 | Wild type | 15.4 |
HuH-7 | Wild type | 4.3 |
Ishikawa | Wild type | 11.3 |
JHH-7 | Wild type | 8.4 |
JHOM-1 | Wild type | 17.1 |
JHOS-2 | Wild type | 22.5 |
KMRC-20 | Wild type | 12.0 |
KNS-62 | Wild type | 22.4 |
KP-1NL | Mutant | 27.7 |
KP4 | Mutant | 30.0 |
KYSE-150 | Wild type | 23.7 |
LCLC-103H | Wild type | 16.7 |
LK-2 | Wild type | 16.0 |
MIA PaCa-2 | Mutant | 17.0 |
NCI-H1299 | Wild type | 28.8 |
NCI-H838 | Wild type | 24.9 |
OVISE | Wild type | 30.0 |
PaTu-8988T | Mutant | 30.0 |
PC-14 | Wild type | 13.5 |
RD | Wild type | 11.9 |
RKO | Wild type | 16.6 |
RMUG-S | Wild type | 12.1 |
SK-HEP-1 | Wild type | 21.8 |
SW480 | Mutant | 21.8 |
TYK-nu | Wild type | 5.2 |
U-251 MG | Wild type | 15.8 |
VMRC-RCW | Wild type | 9.4 |
IC50 proliferation values of Lys01 correspond to Fig. 1A.