Table 2.

Kinetics of T-cell subsets after a single dose of DMPA in HIV-infected women on effective cART.

Anchor	T-cell subset	Week	N	Median (%)	IQR (Q1, Q3)	p-value1
CD4	CD4+CD25+	0	21	3.42	( 2.02, 5.05 )
		4	21	2.85	( 1.73, 6.25 )	0.533
		12	21	2.84	( 1.63, 4.33 )	0.029
	CD4+FOXP3+	0	21	1.26	( 0.80, 2.73 )
		4	21	1.30	( 0.90, 1.46 )	0.828
		12	21	1.29	( 1.01, 1.80 )	0.511
	CD4+CD25+FOXP3+	0	21	0.41	( 0.17, 0.80 )
		4	21	0.24	( 0.11, 0.62 )	0.176
		12	21	0.33	( 0.13, 0.45 )	0.100
	CD4+CD39+	0	21	10.1	( 5.95, 15.9 )
		4	21	10.1	( 6.31, 13.2 )	0.763
		12	21	11.6	( 7.65, 16.5 )	0.078
	CD4+CD38+HLADR+	0	21	7.52	( 4.19, 9.55 )
		4	21	5.98	( 4.05, 10.1 )	0.206
		12	21	5.65	( 3.35, 9.39 )	0.269
	CD4+TGFB+	0	21	4.32	( 2.66, 6.02 )
		4	21	3.62	( 1.93, 7.96 )	0.334
		12	21	3.08	( 2.30, 5.62 )	0.308
	CD4+IL10+	0	21	4.66	( 3.52, 6.16 )
		4	21	6.01	( 3.41, 7.68 )	0.511
		12	21	5.64	( 3.56, 8.43 )	0.427
	CD4+IL35+	0	21	1.86	( 1.22, 3.36 )
		4	21	1.59	( 0.93, 3.19 )	0.352
		12	21	1.35	( 0.78, 2.08 )	0.024
CD8	CD8+CD25+	0	21	0.39	( 0.23, 0.48 )
		4	21	0.38	( 0.22, 0.57 )	0.427
		12	21	0.34	( 0.14, 0.41 )	0.078
	CD8+FOXP3+	0	21	0.85	( 0.54, 1.04 )
		4	21	0.91	( 0.68, 1.49 )	0.023
		12	21	0.74	( 0.67, 1.43 )	0.176
	CD8+CD25+FOXP3+	0	21	0.07	( 0.03, 0.19 )
		4	21	0.06	( 0.03, 0.27 )	0.388
		12	21	0.08	( 0.01, 0.26 )	0.556
	CD8+CD39+	0	21	3.38	( 2.53, 4.52 )
		4	21	4.20	( 2.37, 4.89 )	0.848
		12	21	3.12	( 2.31, 5.20 )	0.675
	CD8+CD38+HLADR+	0	21	4.47	( 2.35, 5.72 )
		4	21	4.28	( 2.44, 7.26 )	0.300
		12	21	3.79	( 2.47, 5.55 )	0.056
	CD8+TGFB+	0	21	1.26	( 0.74, 1.90 )
		4	21	1.22	( 0.76, 2.02 )	0.159
		12	21	1.18	( 0.60, 1.66 )	0.404
	CD8+IL10+	0	21	1.46	( 1.10, 1.87 )
		4	21	1.53	( 1.13, 2.60 )	0.290
		12	21	1.45	( 1.10, 2.21 )	0.701
	CD8+IL35+	0	21	1.22	( 0.87, 1.61 )
		4	21	1.52	( 0.53, 1.99 )	0.490
		12	21	0.89	( 0.65, 1.83 )	0.500

¹Wilcoxon signed-rank test of changes from baseline.

Bold font highlights significant differences and strong trends.