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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: FEBS J. 2015 Nov 6;283(1):112–129. doi: 10.1111/febs.13556

FIGURE 2.

FIGURE 2

Inhibition of deaminase activity by Vif-, A3G- and A3F-derived peptides. (A) Inhibition of deamination by Vif107-115 peptides in dose-dependent manner. The lower gel represents the negative control using Vif30-39 peptide. NC denotes Negative control; PC denotes Positive control. ND; Not deaminated substrate and D; Deaminated product. (B) The effect of peptides and their concentration on A3G-mediated deamination activity with standard ssDNA substrate (10 fmol). Values were determined as shown in panel A. (C) The effect of Vif107-115 and its mutant-derived peptides. (D) The effect of Vif25-39 and its mutant-derived peptides. Data represent the average of triplicates; SD values were less than ± 2 where not indicated.