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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: FEBS J. 2015 Nov 6;283(1):112–129. doi: 10.1111/febs.13556

FIGURE 8.

FIGURE 8

Conformational plasticity of the VKHH and LYYF motifs in A3F-CTD and Vif. (A) With two molecules in the asymmetric unite two distinct conformations of the VKHH motif region are observed in the A3F-CTD crystal structure (PDB: 4IOU), that are strikingly different from the VKHH motif region in the Vif crystal structure (PDB: 4N9F). The lysine side-chain was modeled into the A3F-CTD structure using PyMOL as it was disordered in the crystal structure. (B) Similar conformational diversity of the LYYF motif is also observed between A3F-CTD and Vif.