Fig 4. Band-pass temporal frequency tuning properties of neurons in mouse LGN.

A) An example of commonly encountered temporal frequency tuning profile (“band-pass”). Open circles indicate mean firing rates, and error bars the SEM across four drifting grating repeats (see Table 1). The black curve shows the best fit of a two-half-Gaussian function. The grey area indicates the SEM of spontaneous activity, with the thinner dark line indicating the mean value. Panels B-E present additional parameters measured from the band-pass subtype that represent 84.5% (49/58) of neurons in the data set. In all cases, the arrows show the median of the distribution. B) Distribution of high₅₀ cut-off, with median 6.0 (5.3, 7.0) Hz. C) Distribution of low₅₀ cut-off, with median 1.40 (1.07, 1.60) Hz. D) Distribution of tuning bandwidth, calculated as the difference between high₅₀ and low₅₀ (range illustrated in red in the inset) with median 4.70 (4.07, 5.60) Hz. E) Distribution of preferred temporal frequency with median 3.2 (2.9, 3.6) Hz.