Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Formation of major products from the reaction of peroxynitrite and guanine residue. The reaction between peroxynitrite (ONOO−) and guanine (G) residue forms 8-nitroguanine (8-nitroG), 8-oxoguanine (8-oxoG), 5-guanidino-4-nitroimidazole (NI) and 2,5-diamino-4H-imidazol-4-one (Iz) and it undergoes hydrolysis to form 2,2,4-triamino-5(2H)-oxazolone (Oz) at physiologic pH
