Table 4.

Effects of single oral pretreatment with 20 mg kg⁻¹ of M-2 or M-3 on blood parameters measured after 90 min of left anterior coronary occlusion and 15 min of reperfusion in rats

Experimental group	Biochemical estimation in rats’ blood serum (mean ± SD)
	Glucose (mg/dL)	Bilirubin (mg/dL)	Creatinine (mg/dL)	Amylase (U/L)	GTP (U/L)	GOT (U/L)	Creatine kinase (U/L)	Urea (mg/Dl)
Intact n = 10	139.6 ± 6.92	<0.5	<0.5	4 323.3 ± 241.9	21.35 ± 1.29	109.8 ± 9.3	216.4 ± 87.7	53.46 ± 2.68
Control n = 4/7	137 ± 31.7	<0.5	<0.5	2 975 ± 697.6	24.8 ± 3.86	109.6 ± 10.3*	384.2 ± 106.8	59.5 ± 0.7
DMSO n = 10/13	137.9 ± 17.6	<0.5	<0.5	2 996 ± 512	23.1 ± 5.86	84.8 ± 13.5	362.7 ± 105.2*	60.3 ± 6.7
M-2 n = 10/12	128.3 ± 20.2	<0.5	<0.5	3 169 ± 1063.8	22 ± 6.53	85.5 ± 24.8	481.2 ± 317.5*	54.6 ± 7.03
M-3 n = 10/12	139.1 ± 12	<.5	<0.5	2 779 ± 627.4	20.2 ± 4.8	64.1 ± 18	184.7 ± 88	60 ± 3.82

Bilirubin and creatinine were below detection limit. For other details see Table 1 and text. The differences in blood parameters was calculated using non-parametric Kruskal–Wallis ANOVA test with appropriate post hoc test

Values marked with * p < 0.05 are significantly different from the values of M-3 group