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. 2015 Nov 13;65:103–114. doi: 10.1007/s00011-015-0893-y

Table 1.

Clinical and biochemical parameters in four groups of rats

Group Glu (mmol L−1) BW (g) KW/BW (g/100 g) UAERa (mg·24 h−1)
Normal 6.88 ± 0.81 351.6 ± 15.40 0.30 ± 0.04 0.29×/÷1.1
Control diabetic 26.80 ± 2.98** 224.2 ± 13.20** 0.51 ± 0.04* 0.95×/÷1.2**
Control diabetic + FK506 0.5 mg/kg 27.10 ± 2.44** 227.8 ± 12.64** 0.46 ± 0.05* 0.78×/÷1.1*,#
Control diabetic + FK506 1.0 mg/kg 27.22 ± 2.35** 258.2 ± 18.87** 0. 34 ± 0.06# 0.55×/÷1.1**,##

Data are expressed as mean ± SEM. Number of rats in each group was 10. A shown as geometric mean tolerance factor

Glu glucose, BW body weight, KW/BW kidney-to-body weight ratio, UAER urinary albumin excretion rate

p < 0.05 compared with normal group; ** p < 0.01 compared with normal group; # p < 0.05 compared with control diabetic group; ## p < 0.01 compared with control diabetic group