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. 2015 Oct 8;39:45–57. doi: 10.1007/s40264-015-0352-2

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Distribution of ATC classes for the 345 drugs for which drug–drug-event associations were derived from the electronic health record (EHR) by Iyer et al. [19]. The horizontal axis shows the number of drugs classified in each anatomical (1st level) and therapeutic (2nd level) class (multiple classifications are possible). Of the 345 drugs, 67 belong to the nervous system (N) and another 67 to the cardiovascular system (C) class. At the therapeutic level, the class with most drugs in the set (49) is antineoplastic agents (L01, in light blue)