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. 2015 Sep 11;12(1):42–48. doi: 10.3988/jcn.2016.12.1.42

Table 2. Sensitivity, specificity, positive predictive value (PPV) and level of agreement (κ) for stroke diagnosis.

Sensitivity, % (95% CI) Specificity, % (95% CI) PPV, % (95% CI) κ (95% CI)
JNUH
 Algorithm 1: using all diagnoses
  IS (n=461) 97 (95-98) 88 (85-91) 88 (84-90) 0.84 (0.81-0.87)
  ICH (n=126) 92 (86-96) 96 (95-97) 78 (71-85) 0.82 (0.77-0.87)
  SAH (n=63) 91 (80-96) 98 (97-99) 78 (67-87) 0.83 (0.76-0.90)
  Overall κ 0.81 (0.80-0.83)
 Algorithm 2: using one primary diagnosis and one secondary diagnosis
  IS (n=461) 92 (89-95) 91 (88-93) 90 (86-92) 0.83 (0.79-0.86)
  ICH (n=126) 73 (65-81) 98 (97-99) 85 (77-91) 0.76 (0.69-0.82)
  SAH (n=63) 87 (77-94) 99 (98-99) 81 (70-89) 0.83 (0.76-0.90)
  Overall κ 0.80 (0.77-0.81)
 Algorithm 3: using only one primary diagnosis
  IS (n=461) 67 (62-71) 97 (95-98) 95 (92-97) 0.65 (0.60-0.69)
  ICH (n=126) 60 (51-69) 99 (98-100) 91 (83-96) 0.69 (0.62-0.76)
  SAH (n=63) 73 (60-83) 99 (98-100) 85 (73-93) 0.77 (0.69-0.86)
  Overall κ 0.62 (0.60-0.63)
SMC
 Algorithm 1: using all diagnoses
  IS (n=507) 96 (93-97) 68 (63-73) 82 (79-85) 0.67 (0.61-0.72)
  ICH (n=145) 97 (92-99) 98 (96-99) 90 (84-94) 0.92 (0.88-0.95)
  SAH (n=50) 98 (89-100) 99 (98-100) 88 (76-95) 0.92 (0.86-0.98)
  Overall κ 0.65 (0.62-0.68)
 Algorithm 2: using one primary diagnosis and one secondary diagnosis
  IS (n=507) 86 (83-89) 77 (72-81) 85 (82-88) 0.64 (0.58-0.69)
  ICH (n=145) 92 (86-95) 98 (97-99) 90 (85-94) 0.89 (0.85-0.93)
  SAH (n=50) 98 (94-100) 99 (99-100) 91 (83-98) 0.94 (0.89-0.98)
  Overall κ 0.63 (0.60-0.64)
 Algorithm 3: using only one primary diagnosis
  IS (n=507) 83 (79-86) 84 (80-88) 89 (86-92) 0.66 (0.61-0.71)
  ICH (n=145) 85 (78-90) 99 (97-99) 92 (87-96) 0.86 (0.82-0.91)
  SAH (n=50) 90 (78-96) 99 (98-100) 87 (74-94) 0.88 (0.81-0.95)
  Overall κ 0.65 (0.64-0.69)

CI: confidence interval, ICH: intracranial hemorrhage, IS: ischemic stroke, JNUH: Jeju National University Hospital, SAH: subarachnoid hemorrhage, SMC: Seoul Medical Center.