Table 3. Changes of cognitive subdomains in the rTMS-COG treatment group.
Group | Cognitive domains | Changes of scores, mean (SD) | p value | |||
---|---|---|---|---|---|---|
Δ immediate after treatment | Δ 6 weeks after treatment | [B] vs. [6] | [B] vs. [12] | Time | ||
Treatment | Memory | 2.00 (2.81) | 2.56 (3.05) | 0.040* | 0.006* | 0.054 |
Language | 1.28 (1.53) | 1.44 (1.92) | 0.004* | 0.003* | 0.009* | |
Executive function | 0.67 (1.24) | 0.56 (1.50) | 0.117 | 0.413 | 0.995 | |
Mild treatment | Memory | 1.77 (3.09) | 2.69 (3.17) | 0.275 | 0.031* | 0.178 |
Language | 1.23 (1.79) | 1.23 (1.96) | 0.04* | 0.019* | 0.002* | |
Executive function | 0.92 (1.12) | 0.92 (1.50) | 0.031* | 0.093 | 0.2 | |
Moderate treatment | Memory | 2.60 (2.07) | 2.20 (3.03) | 0.627 | 0.688 | 0.397 |
Language | 1.40 (0.55) | 2.00 (1.87) | 0.243 | 1.000 | 0.947 | |
Executive function | 0.00 (1.41) | 0.40 (1.14) | 1.000 | 0.969 | 0.084 |
Repeatitive measures analysis of covariance including age, gender and duration of education as covariates with multiple comparisons with Bonferroni correction.
*p value<0.05.
rTMS-COG: repetitive transcranial magnetic stimulation with cognitive training, Δ: differences from baseline to at each point, [B]: baseline, [6]: immediately after the end of treatment, [12]: 6 weeks after the end of treatment.