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. 2016 Jan 14;9:153. doi: 10.3389/fncom.2015.00153

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Copyright © 2016 Wang, Yin, Zou, Shu, Rasch and Wu.

This is an open-access article distributed under the terms of theCreative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enhancement of asynchronous release with an increase of U_ar in the SAR model. (A) The IPSCs caused by total transmitter release. (B) The synchronous component of the IPSC caused by synchronous release. (C) The asynchronous IPSC caused by asynchronous release. (D) The internal state u_sr of the synapse model during the spike train. (E) The internal state U_ar during the spike train. (F) The internal state x (with a scale of 1:X_F) during the spike train. Note that asynchronous release causes a decrease in the synchronous release due to the competition of vesicle resources. Parameters: taken from Table 1, except U_ar as indicated. Ax₀ = 10 pA.