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. 2016 Jan 14;9:153. doi: 10.3389/fncom.2015.00153

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Copyright © 2016 Wang, Yin, Zou, Shu, Rasch and Wu.

This is an open-access article distributed under the terms of theCreative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Estimating the receptor decay time constant. The experimental data is from a synapse of epileptic human tissue connecting a fast-spiking interneuron with a pyramidal neuron. Blue curve: the IPSCs. Red curve: the fitted IPSC using an exponential decay function (with offset). (A) A spontaneous release event. The estimated τ_GABA was 4.8 ms (confidence interval 4.39–5.27 ms). (B) Single action potential triggered release. The estimated τ_GABA was 6.2 ms (confidence interval 6.06–6.46 ms).