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. 2015 Dec 8;7(12):1112–1128. doi: 10.18632/aging.100856

Table 1. Effect of rpd3def on longevity of flies on different food levels.

Gender Genotype Food (N) Number Mean Lifespan (% Change to controls) X2 p Maximal Lifespan (% Change)
M +/+ 1.0 261 49.7 71.3 (32)
M rpd3def/+ 1.0 236 70.6 (42) 250.01 <0.001* 93.5 (31)
M +/+ 0.5 261 50.4 64.8
M rpd3def/+ 0.5 247 68.8 (37) 283.64 <0.001* 95.8 (48%)
M +/+ 0.7 263 55.4 73.1
M rpd3def/+ 0.7 243 75.2 (36) 254.15 <0.001* 103.6 (42)
M +/+ 1.5 244 44.4 65
M rpd3def/+ 1.5 254 61.2 (39) 205.28 <0.001* 84 (30)
M +/+ Corn 263 55.7 76
M rpd3def/+ Corn 240 76.5 (37) 243.83 <0.001* 105.3 (39)
F +/+ 1.0 272 54.1 72.6
F rpd3def/+ 1.0 269 70.8 (31) 241.92 <0.001* 95.5 (32)
F +/+ 0.5 264 57.6 72.9
F rpd3def/+ 0.5 259 70.4 (22) 230.55 <0.001* 84.1 (15)
F +/+ 0.7 275 59.8 76.7
F rpd3def/+ 0.7 251 79.6 (33) 317.80 <0.001* 102.8 (34)
F +/+ 1.5 275 46.1 63
F rpd3def/+ 1.5 278 51.5 (12) 37.68 <0.001* 71 (12)
F +/+ Corn 257 60.2 78
F rpd3def/+ Corn 241 62.8 (4) 24.68 <0.001* 88.8 (14)

The mean and maximal lifespan of male (M) and female (F) rpd3def/+ and +/+ control flies on different food levels. All values obtained for controls are compared to values of the rpd3def/+ group of the same sex and on the same food levels to determine the percent increase in mean and maximal lifespan. Food (N): standard food is 1.0N. Number: number of flies used in the experiment. Mean and maximal lifespan are in days. Data are censored for 0-10 days. Long-rank analyses were performed using the JMP 11 program.