Table 2. Effect of DR on longevity of rpd3def/+ (Top) and +/+ control (Bottom) flies.
Gender | Genotype | Food (N) | Number | Mean Lifespan (% Change to controls) | X2 | p | Maximal Lifespan (% Change) |
---|---|---|---|---|---|---|---|
M | rpd3def/+ | 1.0 | 236 | 70.6 | 93.5 | ||
M | rpd3def/+ | 0.5 | 247 | 68.8 (−3) | 3.6229 | 0.57 | 95.8 (2) |
M | rpd3def/+ | 0.7 | 243 | 75.2 (7) | 16.91 | <0.001* | 103.6 (11) |
M | rpd3def/+ | 1.5 | 254 | 61.2 (−13) | 58.619 | <0.001* | 84 (−10) |
M | rpd3def/+ | Corn | 240 | 76.5 (8) | 21.005 | <0.001* | 105.3 (13) |
F | rpd3def/+ | 1.0 | 269 | 70.8 | 95.5 | ||
F | rpd3def/+ | 0.5 | 259 | 70.4 (0) | 4.6814 | 0.0305* | 84.1 (−12) |
F | rpd3def/+ | 0.7 | 251 | 79.6 (12) | 40.489 | <0.001* | 102.8 (8) |
F | rpd3def/+ | 1.5 | 278 | 51.5 (−27) | 266.83 | <0.001* | 71 (−26) |
F | rpd3def/+ | Corn | 241 | 62.8 (−11) | 21.061 | <0.001* | 88.8 (7) |
M | +/+ | 1.0 | 261 | 49.7 | 71.3 | ||
M | +/+ | 0.5 | 261 | 50.4 (1) | 0.3308 | 0.5652 | 64.8 (−9) |
M | +/+ | 0.7 | 263 | 55.4 (11) | 21.498 | <0.001* | 73.1 (3) |
M | +/+ | 1.5 | 244 | 44.4 (−11) | 24.249 | <0.001* | 65 (−9) |
M | +/+ | Corn | 263 | 55.7 (12) | 25.086 | <0.001* | 76 (7) |
F | +/+ | 1.0 | 272 | 54.1 | 72.6 | ||
F | +/+ | 0.5 | 264 | 57.6 (6) | 17.045 | <0.001* | 72.9 (0) |
F | +/+ | 0.7 | 275 | 59.8 (10) | 44.583 | <0.001* | 76.7 (6) |
F | +/+ | 1.5 | 275 | 46.1 (−15) | 62.478 | <0.001* | 63 (−13) |
F | +/+ | Corn | 257 | 60.2 (11) | 52.928 | <0.001* | 78 (7) |
The mean and maximal lifespan of male (M) and female (F) rpd3def/+ (Top) and +/+ control (Bottom) flies on different food levels. All values are compared to values obtained for the flies of the same sex and of the same genotype kept on 1.0N food to determine the percent increase in mean and maximal lifespan. Food N: Number: number of flies used in the experiment. Mean and maximal lifespan are in days. Data are censored for 0-10 days. Long-rank analyses were performed using the JMP 11 program.