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. 2015 Dec 8;7(12):1112–1128. doi: 10.18632/aging.100856

Table 2. Effect of DR on longevity of rpd3def/+ (Top) and +/+ control (Bottom) flies.

Gender Genotype Food (N) Number Mean Lifespan (% Change to controls) X2 p Maximal Lifespan (% Change)
M rpd3def/+ 1.0 236 70.6 93.5
M rpd3def/+ 0.5 247 68.8 (−3) 3.6229 0.57 95.8 (2)
M rpd3def/+ 0.7 243 75.2 (7) 16.91 <0.001* 103.6 (11)
M rpd3def/+ 1.5 254 61.2 (−13) 58.619 <0.001* 84 (−10)
M rpd3def/+ Corn 240 76.5 (8) 21.005 <0.001* 105.3 (13)
F rpd3def/+ 1.0 269 70.8 95.5
F rpd3def/+ 0.5 259 70.4 (0) 4.6814 0.0305* 84.1 (−12)
F rpd3def/+ 0.7 251 79.6 (12) 40.489 <0.001* 102.8 (8)
F rpd3def/+ 1.5 278 51.5 (−27) 266.83 <0.001* 71 (−26)
F rpd3def/+ Corn 241 62.8 (−11) 21.061 <0.001* 88.8 (7)
M +/+ 1.0 261 49.7 71.3
M +/+ 0.5 261 50.4 (1) 0.3308 0.5652 64.8 (−9)
M +/+ 0.7 263 55.4 (11) 21.498 <0.001* 73.1 (3)
M +/+ 1.5 244 44.4 (−11) 24.249 <0.001* 65 (−9)
M +/+ Corn 263 55.7 (12) 25.086 <0.001* 76 (7)
F +/+ 1.0 272 54.1 72.6
F +/+ 0.5 264 57.6 (6) 17.045 <0.001* 72.9 (0)
F +/+ 0.7 275 59.8 (10) 44.583 <0.001* 76.7 (6)
F +/+ 1.5 275 46.1 (−15) 62.478 <0.001* 63 (−13)
F +/+ Corn 257 60.2 (11) 52.928 <0.001* 78 (7)

The mean and maximal lifespan of male (M) and female (F) rpd3def/+ (Top) and +/+ control (Bottom) flies on different food levels. All values are compared to values obtained for the flies of the same sex and of the same genotype kept on 1.0N food to determine the percent increase in mean and maximal lifespan. Food N: Number: number of flies used in the experiment. Mean and maximal lifespan are in days. Data are censored for 0-10 days. Long-rank analyses were performed using the JMP 11 program.