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. 2015 Dec 8;7(12):1112–1128. doi: 10.18632/aging.100856

Table 3. Effect of rpd3P-UTR/+ mutation on longevity of flies on different food levels.

Gender Genotype Food (N) Number Mean Lifespan (% Change to controls) X2 p Maximal Lifespan (% Change)
M rpd3P-1.8/+ 1.0 228 54.2 70.9
M rpd3P-UTR/+ 1.0 219 57.4 (6) 10.212 0.0014 72.61 (2)
M rpd3P-1.8/+ 0.1 70 11.6 15.4
M rpd3P-UTR/+ 0.1 237 17.6 (51) 206.86 <0.001* 26.1 (70)
M rpd3P-1.8/+ 0.3 226 54.5 66.6
M rpd3P-UTR/+ 0.3 206 58.1 (7) 36.901 <0.001* 71.1 (7)
M rpd3P-1.8/+ 0.5 223 58.7 74.4
M rpd3P-UTR/+ 0.5 225 62.4 (7) 23.307 <0.001* 85.7 (15)
M rpd3P-1.8/+ 0.7 227 60.3 75.6
M rpd3P-UTR/+ 0.7 213 58.7 (−3) 5.7376 0.0166* 74.6 3 (−1)
M rpd3P-1.8/+ 1.5 228 58.0 73.5
M rpd3P-UTR/+ 1.5 231 60.0 (3) 4.4888 0.0341* 76.8 (5)
M rpd3P-1.8/+ Corn 227 65.5 87.8
M rpd3P-UTR/+ Corn 218 68.1 (1) 0.0645 0.7995 82.6 (−6)
F rpd3P-1.8/+ 1.0 216 56.2 69.9
F rpd3P-UTR/+ 1.0 223 63.0 (12) 83.590 <0.001* 79.4 (24)
F rpd3P-1.8/+ 0.1 58 15.6 23.2
F rpd3P-UTR/+ 0.1 219 23.6 (52) 120.64 <0.001* 48.7 (110)
F rpd3P-1.8/+ 0.3 225 61.0 78
F rpd3P-UTR/+ 0.3 199 61.9 (2) 9.0925 0.0026 80.7 (4)
F rpd3P-1.8/+ 0.5 224 64.0 77.5
F rpd3P-UTR/+ 0.5 218 72.4 (13) 112.55 <0.001* 89.2 (15)
F rpd3P-1.8/+ 0.7 224 67.3 80.8
F rpd3P-UTR/+ 0.7 232 68.8 (2) 13.142 0.0003* 85.5 ()6
F rpd3P-1.8/+ 1.5 230 56.6 71.4
F rpd3P-UTR/+ 1.5 226 63.0 (10) 60.616 <0.001* 80.6 (13)
F rpd3P-1.8/+ Corn 224 55.0 76.1
F rpd3P-UTR/+ Corn 230 57.0 (4) 24.759 <0.001* 88.8 (17)

The mean and maximal lifespan of male (M) and female (F) rpd3P-UTR/+ and rpd3P-1.8/+ control flies on different food levels. All values for control group are compared to values of rpd3P-UTR/+ flies of the same sex and on the same food levels to determine the percent increase in mean and maximal lifespan. Food (N): standard food is 1.0N. Number: number of flies used in the experiment. Mean and maximal lifespan are in days. Data are censored for 0-10 days except for longevity experiments on 0.1N. Long-rank analyses were performed using the JMP 11 program.