Table 8. 4E-BP mutation affects longevity of rpd3def/+ flies on different food levels.
| Gender | Genotype | Food (N) | Number | Mean Lifespan (% Change to controls) | X2 | p | Maximal Lifespan (% Change) |
|---|---|---|---|---|---|---|---|
| M | Thork07736/+;rpd3def/+ | 1.0 | 256 | 64.3 | 88.8 | ||
| M | Thork07736/+;rpd3def/+ | 0.5 | 259 | 65.9 (2) | 2.1279 | 0.1446 | 87.4 (−2) |
| M | Thork07736/+;rpd3def/+ | 0.7 | 244 | 64.7 (0) | 1.34 | 0.247 | 87.0 (−2) |
| M | Thork07736/+;rpd3def/+ | 1.5 | 228 | 57.1 (−11) | 38.915 | <0.001* | 75.1 (−15) |
| M | Thork07736/+;rpd3def/+ | Corn | 242 | 68.5 (6) | 15.525 | <0.001* | 90.9 (2) |
| F | Thork07736/+;rpd3def/+ | 1.0 | 276 | 64.8 | 89.0 | ||
| F | Thork07736/+;rpd3def/+ | 0.5 | 274 | 68.6 (6) | 8.6198 | 0.0033* | 87.9 (−1) |
| F | Thork07736/+;rpd3def/+ | 0.7 | 275 | 69.9 (8) | 11.562 | 0.0007* | 94.5 (6) |
| F | Thork07736/+;rpd3def/+ | 1.5 | 263 | 49.5 (−24) | 165.63 | <0.001* | 70.1 (−21) |
| F | Thork07736/+;rpd3def/+ | Corn | 258 | 62.2 (−4) | 6.7179 | 0.0095* | 78 (−12) |
The mean and maximal lifespan of male (M) and female (F) Thork07736/+;rpd3def/+ mutant flies on different food levels. All values are compared to flies of the same sex kept on 1.0N food to determine the percent increase in mean and maximal lifespan. Food (N): standard food is 1.0N. Number: number of flies used in the experiment. Mean and maximal lifespan are in days. Data are censored for 0-10 days. Long-rank analyses were performed using the JMP 11 program.