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. 2016 Feb 1;39(2):369–377. doi: 10.5665/sleep.5446

Figure 3.

Figure 3

The distribution of wake bout durations changes between baseline and week 4 after discontinuation of DOX. In the dark (A) and light (B) periods, the proportion of both short and long wake bouts decreases with DOX removal while the proportion of intermediate length bouts increases. In the dark period, differences are significant for all bins except 40–44 sec and 1004–2000 sec (z-test, P < 0.05). In the light period, all differences are significant (z-test, P < 0.01). At baseline, DTA mice averaged 40 wake bouts in the dark period and 100 wake bouts in the light period. At week 4, DTA mice averaged 106 wake bouts in the dark period and 110 wake bouts in the light period.