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. 2016 Jan 14;14:1. doi: 10.1186/s12953-016-0090-0

Table 2.

IC 50 values of the synthetic analogues of natural BPPs for the angiotensin converting enzyme

Peptide Sequence Calculated pI value IC 50 (μM)
Inhibitor 1 (P6) ZLWPRPQXPP 9.75 0.64
Inhibitor 2 (P7) ZQWAQGRAPHPP 9.78 3.63
Inhibitor 3 (P5) ZSAPGNEAXPP 3.99 30.00
Inhibitor 4 (P3) ZNWPHPQXPP 6.74 0.76

Z in stands for pyroglutamate; X refers to isoleucine/leucine