Fig. 4. Perioperative changes of hemodynamic variables. (A) Systolic blood pressure. (B) Diastolic blood pressure. (C) Heart rate. Group D, dexmedetomidine group; Group C, control group; T1, baseline; T2, induction of anesthesia; T3, beginning of surgery; T4, discontinuation of anesthetics; P1, arrival at post-anesthetic care unit (PACU); P2, 10 min after arrival at PACU; P3, 20 min after arrival at PACU. ^*P<0.05 compared to group C. Overall hemodynamic changes over time demonstrated significantly lower systolic and diastolic blood pressures and heart rate in group D compared to group C (P values are in the order of <0.001, 0.001, 0.005).