Table 4. Plasma chemistry and potassium and magnesium replacement in the patients.
Patients | Mutated genes | Number of mutated SLC12A3 |
Number of mutated CLCNKB |
[K+] | [Mg2+] | K+ replacement (mM/d) | Mg2+ replacement (mM/d) | Potassium-sparing diuretics (mg/d) |
---|---|---|---|---|---|---|---|---|
1 | SLC12A3 | 2 | 0 | 3.5 | 0.83 | 24 | 0 | 0 |
2 | SLC12A3 | 2 | 0 | 4.3 | 0.71 | 48 | 0 | 0 |
3 | SLC12A3 | 2 | 0 | 4.1 | 0.75 | 64 | 0 | 0 |
4 | SLC12A3 | 2 | 0 | 4.5 | 0.67 | 120 | 59 | Spironolactone 50 |
5 | SLC12A3 | 2 | 0 | 3.5 | 0.63 | 120 | 235 | Spironolactone 25 |
6 | SLC12A3 | 2 | 0 | 3.3 | 0.88 | 96 | 39 | Spironolactone 50 |
7 | SLC12A3 | 2 | 0 | 5.0 | 0.88 | 168 | 0 | 0 |
8 | SLC12A3 | 2 | 0 | 3.2 | 0.54 | 48 | 0 | Spironolactone 50 |
9 | SLC12A3 | 2 | 0 | 4.6 | 0.71 | 72 | 39 | 0 |
10 | SLC12A3 | 2 | 0 | 3.7 | 0.71 | 240 | 59 | Spironolactone 50 |
11 | SLC12A3 | 2 | 0 | 3.6 | 0.50 | 200 | 59 | Spironolactone 50 |
12 | SLC12A3 | 2 | 0 | 4.0 | 0.54 | 96 | 118 | 0 |
13 | SLC12A3 | 2 | 0 | 4.2 | 0.54 | 96 | 59 | 0 |
14 | SLC12A3 | 2 | 0 | 3.2 | 0.63 | 128 | 118 | Spironolactone 25 |
15 | SLC12A3 | 2 | 0 | 3.1 | 0.58 | 96 | 88 | Spironolactone 25 |
16 | SLC12A3 | 2 | 0 | 4.2 | 0.79 | 48 | 0 | Spironolactone 50 |
17 | SLC12A3 | 2 | 0 | 2.9 | 0.54 | 160 | 0 | Spironolactone 25 |
18 | SLC12A3 | 2 | 0 | 3.1 | 0.46 | 360 | 352 | Spironolactone 50 |
19 | SLC12A3 | 2 | 0 | 3.5 | 0.63 | 48 | 176 | Spironolactone 25 |
20 | SLC12A3 | 2 | 0 | 3.0 | 0.63 | 128 | 0 | Spironolactone 25 |
21 | SLC12A3 | 2 | 0 | 3.4 | 0.63 | 120 | 0 | Spironolactone 50 |
22 | SLC12A3 | 2 | 0 | 3.6 | 0.46 | 112 | 392 | 0 |
23 | SLC12A3 | 2 | 0 | 3.3 | 0.58 | 72 | 118 | 0 |
24 | SLC12A3 | 1 | 0 | 3.5 | 0.67 | 120 | 118 | Spironolactone 50 |
25 | SLC12A3 | 1 | 0 | 3.4 | 0.67 | 160 | 20 | Spironolactone 50 |
26 | SLC12A3 | 1 | 0 | 3.5 | 0.71 | 48 | 39 | 0 |
27 | SLC12A3 | 1 | 0 | 3.7 | 0.83 | 72 | 0 | Spironolactone 50 |
28 | SLC12A3 | 1 | 0 | 2.8 | 1.08 | 180 | 0 | 0 |
29 | SLC12A3 | 1 | 0 | 3.3 | 0.71 | 0 | 0 | 0 |
30 | SLC12A3 + CLCNKB | 1 | 1 | 3.1 | 0.58 | 480 | 881 | Amiloride 20 |
31 | SLC12A3 + CLCNKB | 1 | 2 | 3.8 | 0.79 | 272 | 0 | Spironolactone 50 |
32 | CLCNKB | 0 | 2 | 4.3 | 0.79 | 160 | 0 | Amiloride 5 |
33 | CLCNKB | 0 | 2 | 4.0 | 0.92 | 120 | 0 | 0 |
34 | CLCNKB | 0 | 1 | 3.9 | 0.71 | 72 | 0 | 0 |
[K+], serum potassium concentration (mM/L); [Mg2+], serum magnesium concentration (mM/L).