Table 3. Comparison of the VTE incidence according to chemoprophylaxis use after hip and knee replacement.
| Type of surgery | VTE | DVT | PE | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Chemoprophylaxis | P value* | Chemoprophylaxis | P value* | Chemoprophylaxis | P value* | ||||
| (-) | (+) | (-) | (+) | (-) | (+) | ||||
| Hip (n = 22,127) | 274 (2.0%) | 579 (7.0%) | < 0.001 | 177 (1.35%) | 420 (5.1%) | < 0.001 | 121 (0.9%) | 206 (2.5%) | < 0.001 |
| Primary hip hemiarthroplasty | 198 (2.4%) | 374 (8.5%) | < 0.001 | 116 (1.4%) | 242 (5.5%) | < 0.001 | 102 (1.2%) | 164 (3.7%) | < 0.001 |
| Primary total hip arthroplasty | 58 (1.4%) | 145 (5.0%) | < 0.001 | 46 (1.1%) | 127 (4.4%) | < 0.001 | 15 (0.4%) | 27 (0.9%) | 0.002 |
| Revision total hip arthroplasty | 13 (1.5%) | 45 (7.6%) | < 0.001 | 11 (1.3%) | 40 (6.8%) | < 0.001 | 3 (0.4%) | 9 (1.5%) | 0.016 |
| Knee (n = 52,882) | 406 (1.5%) | 1,584 (6.2%) | < 0.001 | 326 (1.2%) | 1,373 (5.4%) | < 0.001 | 103 (0.4%) | 252 (1.0%) | < 0.001 |
| Unilateral primary total knee arthroplasty | 250 (1.6%) | 869 (6.8%) | < 0.001 | 201 (1.3%) | 765 (5.9%) | < 0.001 | 58 (0.4%) | 128 (1.0%) | < 0.001 |
| Bilateral primary total knee arthroplasty | 132 (1.4%) | 653 (5.8%) | < 0.001 | 107 (1.1%) | 556 (5.0%) | < 0.001 | 36 (0.4%) | 113 (1.0%) | < 0.001 |
| Primary unicompartmental knee arthroplasty | 2 (0.3%) | 12 (2.1%) | 0.002† | 2 (0.3%) | 9 (1.6%) | 0.014† | 0 (0.0%) | 4 (0.7%) | 0.038† |
| Revision knee arthroplasty | 20 (2.4%) | 37 (5.9%) | < 0.001 | 14 (1.7%) | 31 (5.0%) | < 0.001 | 9 (1.1%) | 6 (1.0%) | 0.802 |
| Overall (n = 75,009) | 680 (1.7%) | 2,163 (6.4%) | <0.001 | 503 (1.2%) | 1,793 (5.3%) | <0.001 | 224 (0.5%) | 458 (1.4%) | <0.001 |
*Chi-square homogeneous test for comparing the incidence between chemoprophylaxis (-) group and chemoprophylaxis (+) group; †Fisher' exact test. VTE, Venous thromboembolism; DVT, Deep vein thrombosis; PE, Pulmonary embolism.