Fig. 6.

Antitumoral effects of PEBP in BALB/c mice model with 4T1 cell challenge. Tumor volume (a), tumor weight (b), mammospheres formation from primary tumor cells (c) and metastasis present in lungs (d) of mice that received a 2-week pre-treatment and a 3-week post-inoculation treatment with either polyphenol-enriched blueberry preparation (PEBP) or normal blueberry juice (NBJ) incorporated in drinking water at concentrations of 12.5 % (NBJ 12.5 % and PEBP 12.5 %), 25 % (NBJ 25 % and PEBP 25 %), and 50 % (NBJ 50 % and PEBP 50 %). All values are means of 2 separated experiments ±SEM (n = 16). *Denotes statistical significance at p ≤ 0.05 vs. control