Table 2.
Sample characteristics at enrollment across sites
| Characteristics | Cincinnati (n=15) | Indiana University (n=52) | p-value |
|---|---|---|---|
| Demographics | |||
| Age (years), mean (SD) | 8.56 (1.77) | 8.24 (1.84) | .56 |
| Sex, n (%) male | 11 (73.33) | 44 (84.62) | .44a |
| Group, n (%) Cycloserine | 8 (53.33) | 26 (50.00) | .82 |
| Clinical Variables | |||
| Stanford-Binet V, mean (SD) | |||
| Full Scale IQ | 87.86 (13.78) | 90.40 (17.67) | .62 |
| NonVerbal IQ | 92.57 (15.36) | 93.10 (17.17) | .92 |
| Verbal IQ | 85.29 (14.19) | 88.92 (18.94) | .51 |
| VABS-II Expressive Language subscale standard score, mean (SD) | 84.67 (9.76) | 86.37 (15.21) | .68 |
| Clinical Global Impression-Severity | 4.00 (0.00) | 4.06 (0.24) | .38 |
| Diagnosis, n (%) | |||
| PDD-NOS | 9 (60.00) | 18 (34.62) | .08 |
| Autistic Disorder | 4 (26.67) | 4 (7.69) | .07a |
| Asperger’s Disorder | 2 (13.33) | 30 (57.69) | .003a* |
| Concomitant medications, n (%) | |||
| Antipsychotics | 2 (13.33) | 14 (26.92) | .49a |
| Alpha-2 Agonists | 3 (20.00) | 11 (21.15) | 1.00a |
| Stimulants | 8 (53.33) | 17 (32.69) | .15 |
| Sleep Aids | 3 (20.00) | 13 (25.00) | 1.00a |
| Mood Stabilizers | 0 (0.00) | 3 (5.77) | 1.00a |
| Glutamatergic Modulators | 0 (0.00) | 1 (1.92) | 1.00a |
| Other | 1 (6.67) | 3 (5.77) | 1.00a |
| Concomitant treatment, n (%) | |||
| Speech Therapy | 6 (40.00) | 30 (57.69) | .23 |
| Occupational Therapy | 6 (40.00) | 21 (40.38) | .98 |
| Behavioral Therapy | 2 (13.33) | 16 (30.77) | .32a |
| Other Psychotherapy | 0 (0.00) | 3 (5.77) | 1.00a |
| Physical Therapy | 1 (6.67) | 1 (1.92) | .40a |
| Social Skills Training | 1 (6.67) | 4 (7.69) | 1.00a |
| Music Therapy | 1 (6.67) | 0 (0.00) | .22a |
| Other Treatments | 1 (6.67) | 2 (3.85) | .54a |
a: Fisher’s Exact Test