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. Author manuscript; available in PMC: 2016 Mar 24.
Published in final edited form as: Nature. 2015 Sep 16;525(7570):528–532. doi: 10.1038/nature15367

Extended Data Figure 2. Antibiotic treatment efficiently depletes and alters the composition of the microbiota.

Extended Data Figure 2

a, Copy numbers of 16S ribosomal DNA in feces from control and antibiotics (ABX)-treated mice (n = 5 mice). b, Principal component analysis of the microbiome composition in control and ABX-treated mice (n = 5 mice). c–d, Percentage of each bacteria genus in total microbiome (n = 5 mice). Error bars, mean ± s.e.m. * P < 0.05, *** P < 0.001, data representing ≥2 independent experiments analysed with unpaired Student’s t-test (a, d) or permutational multivariate ANOVA (b).