Figure 1a.

Tree predicting no heavy drinking days during the last 8 weeks of follow-up pruned at α = .00001 in the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) Study training sample (N = 769). ^aN = number of subjects; ^bN with NHDD = number of subjects with no heavy drinking days during the last 8 weeks of the 1-year follow-up; ^c% with NHDD = percentage of subjects with no heavy drinking days during the last 8 weeks of the 1-year follow-up; ^dabstinence at end of treatment = no drinking during the last 8 weeks of the 16-week double-blind treatment period; ^egood clinical outcome at end of treatment = moderate drinking without problems. Moderate drinking was defined as a maximum of 11 drinks (for women) or 14 drinks (for men) per week, with no more than 2 days on which more than 3 drinks (for women) or 4 drinks (for men) were consumed. Problems were defined as endorsing three or more items on a standardized questionnaire assessing physical, social, and psychological consequences of drinking.